Dr. Koushik Das

Assistant Professor

Total years in experience: 5 Post-Ph.D. years

Papers published in journals: 12

Papers presented in conferences: 6

Citations: 57

Academic Background

Bachelor of Science (B.Sc), Microbiology, The University of Burdwan

Master of Science (M.Sc), Microbiology, Bangalore University

Doctor of Philosophy (Ph.D.), Microbiology, The University of Calcutta

Honours and Achievements:

Recipient of Postdoctoral Fellowship from Tokyo Biomedical Research Foundation (TBRF), Tokyo, Japan in 2017.
Recipient of Postdoctoral research residentship from Japan Agency for Medical Research and Development (AMED), Tokyo, Japan in 2015.
Recipient of Senior Research Fellowship from Indian Council of Medical Research (ICMR), India in 2013.
Recipient of International Congress of Parasitology (ICOPA) Travel Award from Japanese Society of Parasitology (JSP), Japan in 2018.

Research:

Contribution: He is currently investigating the project entitled as “Studyof exosomes and pathogen secreted host immunomodulatory molecules for development of future therapeutics against enteric pathogens”, funded by Japan Agency for Medical Research and Development (AMED). Amoebiasis caused by the enteric pathogen Entamoeba histolytica is one of the major enteric diseases in humans.
Interests: To understand in depth molecular basis of host-pathogen interaction, and to identify and validate novel therapeutics targets against enteric pathogens through state of art molecular biology, cell biology, immunology, biochemical and bioinformatics approaches.

Recent Publications:

Das K, Nair L V, Ghosal A, Sardar S, Dutta S and Ganguly S: Genetic characterization reveals evidence for an association between water contamination and zoonotic transmission of a Cryptosporidium sp. from dairy cattle in West Bengal, India. Food and Waterborne Parasitology., e00064 (2019).
Das K, Nozaki T: Non-vesicular lipid transport machinery in Entamoeba histolytica. Front. Cell. Infect. Microbiol., 8:315 (2018).
Das K., Chowdhury P., Nozaki T. and Ganguly S.: Genetic characterization of Entamoeba histolytic reveals a significant association of parasite genotype with disease outcome. J Adv. Biotechnol., 6:798-806 (2016).
Das K, Chowdhury P., Ganguly S.: Internal Transcribed Spacer 1 (ITS1) based sequence typing reveals phylogenetically distinct Ascaris population. Comp Struc Biotech J., 13:478-483 (2015).
Das K, Ganguly S: Evolutionary genomics and population structure of Entamoeba histolytica. Comp Struc Biotech J., 12: 26-33 (2014).
Das K, Mukherjee AK, Chowdhury P, Sehgal R, Bhattacharya MK, Hashimoto T, Nozaki T, Ganguly S: Multilocus sequence typing system (MLST) reveals a significant association of Entamoeba histolytica genetic patterns with disease outcome. Parasitol. Int., 63:308–314 (2014).
Mukherjee AK, Chowdhury P, Das K, Raj D, Karmakar S, Ganguly S: Helminth burden among school going children of southern Bengal, India: A survey report. G.J.B.A.H.S., 2(3): 189-191 (2013).
Ghosh A, Karmakar S, Mukherjee AK, Raj D, Das K, Sarkar S, Nozaki T, Ganguly S: The spliceosomal protein SnRNP F binds to both U3 and U14 class of snoRNA in Giardia lamblia. G.J.B.A.H.S., 2(3): 178-184 (2013).
Mukherjee AK, Das K, Bhattacharya MK, Nozaki T, Ganguly S: Trend of Entamoeba histolytica infestation in Kolkata. Gut Pathogens.,2:12 (2010).
Chatterjee S.N, Das D, Ghosh T.S, Sen T, Das K and Dangar T. K Physico-chemical and Bacteriological Examination of River the Ganga around Sheoraphuli, Hooghly, W.B., India. Journal of Industrial Pollution Control., 26 (1): 35-37 (2010).
Das K and Nozaki T: A novel pathogen-secreted lysine (K) and glutamic acid (E) rich protein 2 (KERP2) from Entamoeba histolytica infiltrates the host nucleus and regulates the host-pathogen relationship. Cell Host & Microbe (under review) (2020).
Das K and Nozaki T: Lipid transfer protein (LTP): single regulator of receptor mediated endocytosis and exocytosis in enteric pathogen Entamoeba histolytica. Nature Commun. (under review) (2020).

Projects:

“Exploitation of lipid metabolism and intracellular lipid transport machinery for the drug development against enteric pathogens” Funded by Tokyo Biochemical Research Foundation (TBRF), Japan.
“Study of exosomes and pathogen secreted host immunomodulatory molecules for development of future therapeutics against enteric pathogens” Funded by: Japan Agency for Medical Research and Development (AMED), Japan.
“Evolutionary biology and population genetics study of protozoan parasite, Entamoeba histolytica.” Funded by: Japan Health Sciences Foundation, Japan.

Ph.D. students guided:

Completed: 1

Ongoing: 1

Books Published:

Das K and Nozaki T. Parasite secretory molecules in host-parasite interaction. In: Eukaryome impact on human intestine homeostasis and mucosal immunology. Nancy Guillen (eds). Springer. (2020).

Professional Memberships/Fellowship: