Faculty Department

Dr. Snigdha Mishra

Assistant Professor-Selection Grade

Ph.D ( Biological Sciences) awarded by Academy of Scientific and Innovative Research (AcSIR), New Delhi. GPA: 7.5/10. Thesis: “Development of Drosophila as an alternative to animal models for assessment and understanding of male reproductive toxicity of xenobiotics” (2010-2015)

Master of Science (Biotechnology) from H.N.B Garhwal University, Srinagar, Uttarakhand. Percentage of marks: 78.26% (2006-2008)

Area of Interests:

• Molecular Biology, Recombinant DNA Technology and Genetics; Developmental Biology; Drosophila Research in Reproductive Biology and endocrinology

Career Graph:

• Assistant Professor-SG, University of Petroleum and Energy Studies (UPES)- School of Health Sciences and Technology, Dehradun (2022-present)
• Post doctoral Research Associate at Wolfner lab, Dept of Molecular Biology and Genetics, Cornell University, Ithaca, NY-14850, USA ( 10/2018-11/2021 ) Mentor: Mariana. F.  Wolfner
  Research Area: Reproductive Biology
• Research Associate at National Institute of Research in Reproductive Health, NIRRH (ICMR) Mumbai, India ( 03/2016-06/2016)
  Research Project: “Identification and development of a potential stem cell growth factor from the peri-vitelline fluid for its application in Stem Cell Research”
• Senior Research Fellow, Council of Scientific and Industrial Research (CSIR), Indian Institute of Toxicology Research, Lucknow, India. Mentor (PhD supervisor): Dr. Ravi Ram Kristipati ( 01/2012-12/2014 )
• Junior Research Fellow, Council of Scientific and Industrial Research (CSIR), Indian Institute of Toxicology Research, Lucknow, India. Mentor (PhD supervisor): Dr. Ravi Ram Kristipati ( 01/2010-01/2012 )

Papers published in international journals: 7

Papers presented in conferences: 35

Citations: 180

H-index: 6, i10-index: 6

Research interests: Reproductive Biology, Fruitfly Genetics

Recent Publications:

• Nora C. Brown1, Snigdha Misra1, Benjamin Gordon1,2, Caitlin E. McDonough-Goldstein3, , Geoffrey D. Findlay1,4, Andrew G. Clark*1, Mariana F. Wolfner*1. The seminal odorant binding protein Obp56g is required for mating plug formation and male fertility in Drosophila melanogaster. Under review in Elife (IF-8.7)
• Snigdha Misra, Norene A. Buehner, Akanksha Singh, MF Wolfner. Female factors modulate Sex Peptide’s association with sperm in Drosophila melanogaster BMC Biol, 2022, 20:279 (IF-7.4)
• Snigdha Misra, MF Wolfner. Drosophila seminal sex peptide associates with rival as well as own sperm, providing SP function in polyandrous females. Elife 9, 2020, e58322 (IF-8.7)
• Snigdha Misra, Anuj Kumar Pandey, Snigdha Gupta, Ajay Kumar, Priyanka Khanna, Jaishankar, Ravi Ram Kristipati. Estrogen related receptor is required for the testicular development and for the normal sperm axoneme/mitochondrial derivatives in Drosophila males. SCIENTIFIC REPORTS, 2017| 7:40372  (IF-5.0)
• Snigdha Misra, Anshuman Singh, Chintapalli Ratnasekhar, Vandana Sharma, Mohana Krishna Reddy Mudiam  and Kristipati Ravi Ram. Identification of Drosophila based endpoints for the assessment and understanding of xenobiotic mediated male reproductive adversities. TOXICOLOGICAL SCIENCES, 2014, 141(1), 278–291 (IF-4.1)
• This work (Tox sci 2014) has been included in, OECD and Environment Protection Agency (EPA) documents on final scope of risk evaluation and assessment for Dibutyl phthalate.
• Snigdha Misra, Ajay Kumar, CH Ratnasekhar, Vandana Sharma, Mohan Krishna Reddy Mudiam, Kristipati Ravi Ram. Exposure to endosulfan influences sperm competition in Drosophila. SCIENTIFIC REPORTS, 2014| 4 : 7433  (IF-5.0)
• Vandana Sharma, Anuj Kumar Pandey, Ajay Kumar, Snigdha Misra, Himanshu P K Gupta, Snigdha Gupta, Anshuman Singh, Norene A Buehner, Kristipati Ravi Ram. Functional male accessory glands and fertility in Drosophila require novel ecdysone receptor. PLoS GENETICS, 2017, 1006788 (IF-6.0)
• Stuart Wigby†, Nora C. Brown†, Sarah E. Allen,Snigdha Misra, Jessica L. Sitnik‡, Irem Sepil, Andrew G. Clark and Mariana F. Wolfner. The Drosophila seminal proteome and its role in postcopulatory sexual selection. Philosophical Transactions of the Royal Society B: Biological Sciences, 2020, Vol. 375, Issue. 1813 (IF-6.7)

Book Chapter

• Misra S, Allen SE, Chen DS and Wolfner MF. Seminal metalloproteas-1. In N.D Rawlings & D. Auld (Eds.), Handbook of Proteolytic enzymes (4th ed.). Academic Press. In press

Professional Memberships/Fellowships/Awards:

• 2018-present Genetics Society of America (GSA), USA

Science outreach and Services

• 2019-present : Volunteer Teacher at eVidyalok foundation ; Reviewer for Chemosphere, IBMB, IMB; Poster session judge for GSA held ADRC, USA

Honours and Achievements:

• 2009 :  Qualified National Eligibility Test-NET (Sub: Lifesciences) for the award of Junior Research Fellowship, CSIR, India, with an AIR of 239
• 2009 :  Qualified Graduate Aptitude Test in Engineering-GATE (Sub: Lifesciences) with 91.25 percentile.
• 2010 :  Junior Research Fellowship, CSIR- Indian Institute of Toxicology Research, INDIA
• 2012 :   Senior Research Fellowship, CSIR- Indian Institute of Toxicology Research, INDIA
• 2020-22 : Poster presentation at 61st, 62nd and 63rd Annual Drosophila Research conference (Virtually held)
• 2019 : Poster presentation at 60th Annual Drosophila Research conference, Dallas, Texas, USA