Shraddha Manish Gupta

Assistant Professor

Ph.D. (Pursuing since 2018) – Doctoral thesis research on ‘Development of Newer Anti- Alzheimer’s Agent Based on Indene Scaffold’ under the supervision of Dr. Neetesh Jain and Dr. Ashok Behera.

Master of Pharmacy (2006 August) – Pharmaceutical Chemistry - N.D.M.V.P.S. College of Pharmacy, Gangapur Road, Nashik- 422429, Maharashtra, India (Pune University)

Bachelor of Pharmacy (2003 June) - N.D.M.V.P.S. College of Pharmacy, Gangapur Road, Nashik- 422429, Maharashtra, India (Pune University)

Career Graph:

Assistant Professor (March 2022 – continue), School of Health Sciences and Technology, University of Petroleum and Energy Studies.
Assistant Professor, Department of Pharmacy, DIT University, Dehradun. (Sept. 2018- 2021)
Research Assistant, Monash University, Malaysia. (Aug.2017-Aug.2018)
Senior Assistant Professor, Modern Institute of Pharmaceutical Sciences, Indore (Aug. 2011- Nov.2012)
Assistant Professor, NMIMS Deemed University School of Pharmacy and Technology, Shirpur. (July2010-Feb.2011)
Assistant Professor, B M College of Pharmaceutical Education and Research Village, Indore, Madhya Pradesh (Sept. 2009- Apr. 2010)
Lecturer, MGV’s SPH college of Pharmacy, Maharashtra (Sept. 2006- June 2009)
Assistant Lecturer, SSDJ College of Pharmacy, Maharashtra (Sept. 2003- July. 2004

Papers published in journals: 7

Papers presented in conferences: 3 (International conferences), 11 (national conferences)

International:

Shraddha M Gupta, Ashok Behera, Neetesh K Jain’In-silico identification, and characterization of Indene analogues targeting acetylcholinesterase for Alzheimer’s disease.’ at Monash University, Malaysia in MONASH INITIATE 2021 conference (June2021) scientific program.
Shraddha M Gupta, Sushil K Chaudhary, Ashok Behera, Neetesh K Jain2 “Therapeutic efficacy of Hispolon, a polyphenol for management Alzheimer’s Disease” in drug discovery summit-2020 in at international web conference on “Exploring New Horizons in Drug Research, Discovery & Development” on October 9-10, 2020. Conducted by Baddi University in association with Chandigarh Region Innovation and Knowledge Cluster (CRIKC) & CIPLA foundation.
Shraddha M Gupta, Sushil K Chaudhary, Neetesh K Jain “Anti-inflammatory drugs in Alzheimer’s disease: A preclinical analysis” at APTICON-2019 on October 11-13, 2019, at DIT University. India and abstract in International Journal of Pharmaceutical Sciences and Research. Page No: 179

National:

“Effect of Excipients on in-vitro intestinal permeation of Ciprofloxacin” at IPC (Indian Pharmacopeia Commission)- 2003 at Pune (M.S), India
“Synthesis and Antifungal activity of Various Piperazinyl Benzothiazine Derivatives” at IPC-2005 at Hyderabad (A.P.), India
“Synthesis and Antifungal activity of N-(alkyl/aryl)-α-(2,3-dihydro-3-oxo-1,4- Benzothiazine-2-yl) Propionamide Derivatives” at IPC-2007 at Varanasi (U.P.), India
“QSAR (Quantitative Structure Activity Relationship) and Molecular Modelling of novel PIM protein kinase inhibitors” at IPC-2010 at Manipal. India
“Optimization of test masking technique of oral suspension of Cefpodoxime Proxetil” at IPC-2010 at Manipal.India
“Quantitative estimation of Alcohol from marketed herbal formulation by Gas Chromatography” at 3rd IPA convention-2011 at Indore. India
“QSAR and Molecular modelling of novel PIM protein kinase inhibitors” at National Conference on Green Chemistry and Environment, Oct-2011. Indore, India.
“In-Vitro Antioxidant Activity of Curcuma longa” Conference on Advances in Pharmaceutical Research and Chemistry, National Institute of Technical Teachers' Training and Research, Bhopal, India, March 2012.
Poster presentation entitled as: ‘Design, Molecular docking, and in-silico studies of Indene analogues for Alzheimer’s Disease.’ On 5 days national conference on “Recent Advancement in Pharmaceutical Sciences” (18-22 Jan2021) at Devsthali Vidyapeeth College of Pharmacy.
Poster presentation entitled as: “Novel Indole Analogues as Inhibitors of Acetylcholinesterase Enzyme, their Synthesis, Evaluation and Uses Thereof (Patent Application Number: 202211065309)” at International Young Researchers conclave- 2023 organized at UPES (University of Petroleum and Energy Studies) on 19,20 January 2023

Workshops:

Attended workshop on 'Systematic review and Meta-analysis' on Sept 2017 at MONASH University Malaysia.
Attended workshop on 'Scientific writing and Editing' on July 2018 at MONASH University Malaysia.

Research:

Interests:
Computer aided Drug design
Lead Optimization.
Drug repurposing, Novel drug discovery.
Neurodegenerative Disorders, Alzheimer’s Diseases.

.Recent Publications:

Quantification of Ethanol Content in Traditional Herbal Cough Syrups published in Pharmacognosy Journal. DOI: https://doi.org/10.5530/pj.2017.6.128 2017, 9, 6,821-827. IF 1.085
Singh, S., Sanwal, P., Bhargava, S., Behera, A., Upadhyay, S., Akhter, M. H., Gupta, M., & Gupta, Shraddha. M. (2022). Smart Advancements for Targeting Solid Tumors via Protein and Peptide Drug Delivery (PPD). Current Drug Delivery, 10.2174/1567201819666220427132734. Advance online publication. https://www.eurekaselect.com/204141/article, Bentham Scopus, IF 2.565
Shraddha M Gupta, Neetesh K Jain, Rohitash Yadav, Meryem Erol, Ismail Celik, Manish Gupta, Ashok Behera (2022).; Computational investigation of the interaction of novel indene methylene analogs with acetylcholinesterase inhibitors for Alzheimer’s disease: from both dynamics and thermodynamics viewpoint in "Letters in Drug Design & Discovery”, DOI: https://doi.org/10.2174/1570180819666220623144252. Bentham Scopus, IF 1.099, ISBN: 1875-628X (Online)
Quantum Dots in the Biomedical World: A Smart Advanced Nanocarrier for Multiple Venues Application published in Archiv der Pharmazie, DOI: https://doi.org/10.1002/ardp.202200299. IF 4.613
Preclinical models for Alzheimer’s disease: past, present and future approaches published in ACS Omega https://doi.org/10.1021/acsomega.2c05609. IF 4.132
Indene-Derived Hydrazides Targeting Acetylcholinesterase Enzyme in Alzheimer’s: Design, Synthesis, and Biological Evaluation in Pharmaceutics, https://doi.org/10.3390/pharmaceutics15010094, IF 6.525
Shraddha Manish Gupta, Neetesh K Jain, Ashok Behera; "Computational ADME analysis and Antioxidant potential of 5-methoxy-2-methyl-1H-indol-3-yl)-N'- (substituted benzylidene) acetohydrazide derivatives for neuroprotection”. in “Journal of International Academy of Physical Sciences” [ISSN0974-9373] https://www.iaps.org.in/journal/index.php/journaliaps/article/view/952
Sulindac: A review of its Pharmacokinetics, Preclinical and Clinical aspect’ submitted in ChemistrySelect Journal. (Under review).
Current Scenario for the management of type II diabetes through investigation of Conventional & Non-Conventional Pharmacotherapeutic Approaches in Frontiers in Pharmacology Journal. (Under review).

Patent Publications:

Deepika Raina, Siddharth Singh, Shraddha M Gupta; A Diffusing Liquid Composition for Management of Neuropsychiatric Disorders and Methods of Preparation Thereof; Indian patent filling number:202211017553, March26,2022. (published)
Shraddha M Gupta, Neetesh K Jain, Ashok Behera, Devendra Kumar, Dinesh Rishipathak; Indomethacin derivatives as multitargeting agent for Alzheimer's disease management and process for synthesis. Indian patent filling Application Number: 202211065309, November15,2022. (published)

Professional Memberships/Fellowship:

Life Membership of Association of Pharmaceutical Teachers of India (APTI), Membership no: MA/LM-992
Life Membership of Indian Pharmaceutical Association (IPA).
Registered Pharmacist in India. (Registration No: MH-72245)
American Chemical Society (ACS) Community Associate (Membership no: 32382428)
Affiliate Member of Royal Society of Chemistry (RSC), Membership no: 687220. Member of International Pharmaceutical Federation (FIP), Netherland, Membership no: 38626. (2020-2021)
Life Membership of Indian Society of Chemists and Biologists (ISCB) Membership no: LF 1186/2022

Book Chapters

“Nanotechnology-Based Smart Pharmaceutical Nano-carriers for Nutraceutical Delivery” book chapter in entitled book: Naturally Occurring Nutraceuticals in Health Management, Apple Academic Press, CRC Press, (A Taylor & Francis Group), Ontario, Canada in 2023.
Clinical trials, regulatory considerations and Market overview of antibiotics (2023).; accepted in Antibiotics – Therapeutic Spectrum and Limitations, Elsevier.

Honours and Achievements:

Honours:

Secured 3rd prize on Poster presentation entitled as: “Novel Indole Analogues as Inhibitors of Acetylcholinesterase Enzyme, their Synthesis, Evaluation and Uses Thereof (Patent Application Number: 202211065309)” at International Young Researchers conclave- 2023 organized at UPES on 19,20 January 2023
Received certificate of excellence as “Women Researcher Award” at International Research Awards on Science, Health, and Engineering SHEN 2021 Awards
Certificate of appreciation for a Mentor in CSIR-SRTP (2020) program under Interdisciplinary Approach for Sustainable Use of Resources project-13. (From June-August-2020)
Honoured to be a Keynote Speaker on CIIES Webinar at DIT University on: Pharmaceutical Innovation: A Step towards making Atma-Nirbhar Bharat.
Secured 78% (A+) grade in AICTE approved FDP under ARPIT entitled as “Advances in drug discovery and formulation development”. By IIT BHU, Varanasi.
Secured 71% in SWAYAM online certification course on ‘Analytical Techniques’ (15 weeks, 4 credit) offered by AIIMS, New Delhi

Scholarships: